Class 2 Family 5

Family 5 Overview

2 experimentally studied proteins

1 sequence in Swiss-Prot

4,578 unique sequences in UniRef100

Bacterial (mostly bacteroidota) aspartylglucosaminidases

Clan 1: Family 1, Family 2, Family 3, Family 4, Family 5

Reference Monomer¹

Reference Structure

Family 5 Motifs
(Q47898)

Experimentally Studied Proteins

	Fam ? Class - Clan - Family	Alt ? Alternative historical name / classification	AN ? UniProt accession number	Name ? UniProt entry name, only given here for Swiss-Prot entries	EC	Organism	Cell-Loc	AAs	Structure	PDB	K_m i for Asn [mM]	V_max i for Asn [μmol/min/mg]	K_cat i for Asn [s^-1]
	2-1-5	-	A0A1V3U2Z4		3.5.1.26	Elizabethkingia meningoseptica	-	331	Hetero tetramer / homo dimer	6DEY	-	-	-
	2-1-5	-	Q47898	ASPG_ELIMR	3.5.1.26	Elizabethkingia miricola	Periplasm	340	Hetero tetramer / homo dimer	1AYY PDBs	-	-	-

Swiss-Prot Sequences

	Fam ? Class - Clan - Family	Alt ? Alternative historical name / classification	AN ? UniProt accession number	Name ? UniProt entry name, only given here for Swiss-Prot entries	EC	Organism	Cell-Loc	AAs	Structure	PDB	K_m i for Asn [mM]	V_max i for Asn [μmol/min/mg]	K_cat i for Asn [s^-1]
	2-1-5	-	Q47898	ASPG_ELIMR	3.5.1.26	Elizabethkingia miricola	Periplasm	340	Hetero tetramer / homo dimer	1AYY PDBs	-	-	-

UniRef100 Sequences²

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Representative Sequence Alignment

Additional Information

Clan 1 contains five families that are to an extent phylogenetically distinct from the other clans, they have aspartylglucosaminidase (AGA) activity in addition to l‑asparaginase activity.

Family 5 contains the Elizabethkingia miricola AGA (Q47898), for which the protein structure has been solved.

¹Varadi, M et al. AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences. Nucleic Acids Research (2024). Licensed under CC BY 4.0.

²Suzek, B.E. et al. UniRef: comprehensive and non-redundant UniProt reference clusters. Bioinformatics (2007). Licensed under CC BY 4.0. Added classification code to sequence headers.