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Class 2 Family 18

Family 18 Overview

0 experimentally studied proteins

0 sequences in Swiss-Prot

2,456 unique sequences in UniRef100

Putative bacterial (mostly pseudomonadota) isoaspartyl peptidases

Clan 5: Family 13, Family 14, Family 15, Family 16, Family 17, Family 18

Reference Monomer1

mono2-18.png

Reference Structure

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Family 18 Motifs
(A0A7G5IIE2)

motifs2-18

Experimentally Studied Proteins

Swiss-Prot Sequences

UniRef100 Sequences2

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Representative Sequence Alignment

Motifs Image

Additional Information

Clan 5 also holds families of isoaspartyl peptidases.

Family 15–18 consist of bacterial enzymes, many of which have signal sequences. Some sequences in Family 18 consist of both the isoaspartyl peptidase domain and a Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase. Family 18 sequences are mostly from pseudomonadota.

1Varadi, M et al. AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences. Nucleic Acids Research (2024). Licensed under CC BY 4.0.

2Suzek, B.E. et al. UniRef: comprehensive and non-redundant UniProt reference clusters. Bioinformatics (2007). Licensed under CC BY 4.0. Added classification code to sequence headers.


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